Paradox Immunotherapeutics is an Ontario-based pharmaceutical company developing immunotherapies for rare diseases that cause organ failure. Using a proven-successful immunotherapy drug design platform, they design drugs that harness the body’s own immune system to clear lethal deposits from affected organs and reverse organ damage. The company is founded by the same team that designed PRX004, an immunotherapy to treat heart failure caused by transthyretin (ATTR) amyloidosis. PRX004 was licensed to Prothena Biosciences Inc. (So. South Francisco, USA) by University Health Network (Toronto, Canada) and entered FDA clinical trials in 2018 (NCT#03336580). Using the same platform technology, their lead candidate includes a potential treatment for immunoglobulin light chain (AL) cardiac amyloidosis, another cause of heart failure for which no first-line therapy currently exists and a US market opportunity of ~$3.2B. Their other discovery pipelines include treatments for chronic renal failure, ALS, and frontotemporal dementia. With a team of experts in immunotherapy drug design, they possess an orphan drug discovery platform for the potential treatment of ~30 rare diseases, a platform technology which has already sparked the interest of major players in the pharmaceutical industry.
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Well done for the poster prize!
Congrats on the poster prize guys!
Congratulations, Natalie & Yulong! Incredible work and wishing all the success.
Great job on the pitch Natalie!
Would you like to speak with the Paradox Team live? 🎥💻
Please feel free to meet us virtually in our online video room until 5:30pm EST today. Click here! https://zoom.us/j/129181510
Congratulations Paradox on making it through the Synapse Competition! We're all impressed by the commitment and effort that you've put in over the last few months to get to this stage. We hope that participating in the Competition was a valuable experience for you - and remember, there are still lots of ways that Innovation Factory, the Synapse Consortium and the rest of the Hamilton ecosystem can provide support!
Ask the team from Paradox a question, or make a connection by posting a comment!
Watch Paradox Immunotherapeutics' elevator pitch and poster over at www.synapselifescience.com/competition
Click on the Paradox Poster to see a larger view!