Mesosil is a materials science company making responsive additives for dental materials to prevent infection and cavities, the most common medical conditions in the world. Mesosil has developed the first lifetime-effect line of antimicrobial materials to prevent the long-term breakdown, infection, and recurrent disease responsible for up to 70% of treatment failures in dentistry. These improvements will allow for truly permanent solutions that no longer leave teeth and gums vulnerable to bacterial attack. Mesosil’s technology outclasses competitors in two key areas: biostability and antimicrobial efficacy, resulting in an 80% reduction in tooth breakdown and cavitation. These benefits are provided over the total lifespan of the patient, a previously unobtainable timescale, without bacterial resistance development, or changes to the underlying materials used and clinician workflow.